Article

Transcriptome profiling of neurexin- and neuroligin-deficient Caenorhabditis elegans reveals pathways underlying developmental and behavioral dysfunction

2026-07-08

Abstract excerpt

<title>Abstract</title> Neurexins and neuroligins are evolutionarily conserved synaptic adhesion molecules that play essential roles in synapse formation and neural circuit function, with mutations linked to neurodevelopmental disorders such as autism. Here, we combined whole-transcriptome sequencing with phenotypic characterization to define the molecular consequences of neurexin and neuroligin deficiency i...

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Literature Corpus work: 33cdcdc4-6585-5da2-b740-55adccc9adf0
DOI: 10.21203/rs.3.rs-10280322/v1

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