Article

Modelling mental disorders in zebrafish. Neurexins severely modulate anxiety, social behaviours and aggression

2025-11-25

Abstract excerpt

<h4>ABSTRACT</h4> Can we reproduce mental disorders in zebrafish? To explore this question, we manipulated the neurexin gene family. Neurexin ( nrxn ) genes encode synaptic cell-adhesion molecules that have been repetitively associated with neurodevelopmental and mental disorders. While the zebrafish animal model offers tremendous advantages for dissecting neural development/function, no robust nrxn zebrafish m...

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Literature Corpus work: c14f44e2-9322-57c2-bc29-b1f619384f3f
DOI: 10.1101/2025.11.24.690344

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