Article
Genetic subtype classification using a simplified algorithm and mutational characteristics of diffuse large B-cell lymphoma in a Japanese cohort.
British journal of haematology - 1 Dec 2021
Mishina Tatsuzo, Oshima-Hasegawa Nagisa, Tsukamoto Shokichi, Fukuyo Masaki, Kageyama Hajime, Muto Tomoya, Mimura Naoya, Rahmutulla Bahityar, Nagai Yurie, Kayamori Kensuke, Hino Yutaro, Mitsukawa Shio, Takeda Yusuke, Ohwada Chikako, Takeuchi Masahiro, Tsujimura Hideki, Iseki Tohru, Nakaseko Chiaki, Ikeda Jun-Ichiro, Itami Makiko, Yokote Koutaro, Ohara Osamu, Kaneda Atsushi, Sakaida Emiko
Abstract excerpt
Recent large-scale genetic studies have proposed a new genetic classification of diffuse large B-cell lymphoma (DLBCL), which is clinically and biologically heterogeneous. However, the classification methods were complicated to be introduced into clinical practice. Here we retrospectively evaluated the mutational status and copy number changes of 144 genes in 177 Japanese patients with DLBCL, using targeted DNA...
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