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Article

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing

15 Mar 2018

Abstract excerpt

Sexual development in Plasmodium Malaria-causing parasites ( Plasmodium ) have complex life histories in the tissues of humans. For the most part, the parasites focus their efforts on replication within the human host cells. However, occasionally, some replicating cells release gametes into the bloodstream, which are picked up by biting mosquitoes. Filarsky et al. discovered that the Plasmodium parasite keeps the...

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PMID: 29590075
DOI: 10.1126/science.aan6042

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