Article
The HTR1A and HTR1B receptor genes influence stress-related information processing.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2011
Mekli Krisztina, Payton Antony, Miyajima Fabio, Platt Hazel, Thomas Emma, Downey Darragh, Lloyd-Williams Kathryn, Chase Diana, Toth Zoltan G, Elliott Rebecca, Ollier William E, Anderson Ian M, Deakin J F William, Bagdy Gyorgy, Juhasz Gabriella
Abstract excerpt
The serotonergic system has been widely implicated in stress related psychiatric disorders such as depression and anxiety. We investigated the possible association between depression and anxiety scores and SNPs within the HTR1A and HTR1B genes in a population sample (n=1387). There was no direct SNP-phenotype association, but in interaction with recent stressful life events rs6295 G, rs878567 T alleles and rs6296...
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