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Cytogenetic and Molecular Genetic Driven Prediction of Response to First-Treatment and Prognosis in Acute Myeloid Leukemia: A Retrospective Cohort Study.

Genes, chromosomes & cancer - 1 Sept 2025

Zhang Henan, Liu Xuan, Wang Xiaoning, Zhang Qiang, Xin Beibei, Shen Yiyang, He Pengcheng, Zhang Jihong

Abstract excerpt

BACKGROUND: The first induction therapy is critical in determining subsequent treatment strategies and patient outcomes in acute myeloid leukemia (AML). This study aimed to comprehensively analyze the genetic landscape of AML patients to construct risk prediction models for the first-treatment response. METHODS: A total of 921 adult AML patients (Cohort 1) were included to characterize the genetic landscape and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40981232
DOI: 10.1002/gcc.70081

Genes

FLT3
NPM1
TET2
TP53
ASXL1
GATA2
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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