Article
Stochastic galactokinase expression underlies GAL gene induction in a GAL3 mutant of Saccharomyces cerevisiae.
The FEBS journal - 1 Apr 2014
Kar Rajesh Kumar, Qureshi Mohd Tanvir, DasAdhikari Akshay Kumar, Zahir Taiyeb, Venkatesh Kareenhalli V, Bhat Paike Jayadeva
Abstract excerpt
GAL1 and GAL3 are paralogous signal transducers that functionally inactivate Gal80p to activate the Gal4p-dependent transcriptional activation of GAL genes in Saccharomyces cerevisiae in response to galactose. Unlike a wild-type strain, the gal3∆ strain shows delayed growth kinetics as a result of the signaling function of GAL1. The mechanism ensuring that GAL1 is eventually expressed to turn on the GAL switch in...
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