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Article

Angiogenesis pattern and H3.3 histone mutation in aggressive and non-aggressive central giant cell lesions.

Archives of oral biology - 1 Oct 2021

de Oliveira Filho Sérgio Alves, Martins Allisson Filipe Lopes, Mosconi Carla, de Paula Henrique Moura, Mendonça Elismauro Francisco

Abstract excerpt

OBJECTIVE: The aim of this study was to evaluate angiogenesis in central giant cell lesions (CGCL) and its association with biological behavior. In addition, investigation of the histone H3.3 mutation was performed. DESIGN: Thirty-eight cases of CGCL were classified as aggressive (n = 9) or nonaggressive (n = 29). Cases were submitted to immunohistochemistry to compare angiogenesis using Wilms' tumor protein 1...

Topics

Endoglin
Giant Cells
Histones
Humans
Mutation
Neovascularization, Pathologic
Platelet Endothelial Cell Adhesion Molecule-1

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34364170
DOI: 10.1016/j.archoralbio.2021.105218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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