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Article

A tailored histology-driven molecular profiling algorithm proposal for salivary gland cancers

16 Jan 2026

Abstract excerpt

BACKGROUND: Salivary gland cancers (SGCs) are rare, heterogeneous malignancies with limited systemic therapies. This study aimed to define a histology-driven molecular profiling (MP) algorithm for SGCs to optimize testing strategies and support therapeutic decision-making. MATERIALS AND METHODS: We retrospectively analyzed all SGC patients who underwent MP (2016-2023) for gene rearrangements and pathogenic/likely...

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Share to Gene expression and cancer classification
Share to Salivary Gland Disorders and Functions
Share to Salivary Gland Tumors Diagnosis and Treatment

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PMID: 41547215
DOI: 10.1016/j.esmoop.2025.106033

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