Article
Changes in Chromatin Organization Eradicate Cellular Stress Resilience to UVA/B Light and Induce Premature Aging.
Cells - 11 Jul 2021
Vasileva Bela, Staneva Dessislava, Krasteva Natalia, Miloshev George, Georgieva Milena
Abstract excerpt
Complex interactions among DNA and nuclear proteins maintain genome organization and stability. The nuclear proteins, particularly the histones, organize, compact, and preserve the stability of DNA, but also allow its dynamic reorganization whenever the nuclear processes require access to it. Five histone classes exist and they are evolutionarily conserved among eukaryotes. The linker histones are the fifth class...
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