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Article

Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes.

Genes - 20 Jul 2021

Sohn Min-Hwan, Kim Se Ik, Shin Jong-Yeon, Kim Hee Seung, Chung Hyun Hoon, Kim Jae-Weon, Lee Maria, Seo Jeong-Sun

Abstract excerpt

High-grade serous ovarian cancer (HGSOC) is one of the deadliest cancers that can occur in women. This study aimed to investigate the molecular characteristics of HGSOC through integrative analysis of multi-omics data. We used fresh-frozen, chemotherapy-naïve primary ovarian cancer tissues and matched blood samples of HGSOC patients and conducted next-generation whole-exome sequencing (WES) and RNA sequencing...

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Source

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Identifiers

PMID: 34356119
DOI: 10.3390/genes12071103
PMCID: PMC8303300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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