Article
Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.
Cancer letters - 1 Jul 2015
Kreuzinger Caroline, Gamperl Magdalena, Wolf Andrea, Heinze Georg, Geroldinger Angelika, Lambrechts Diether, Boeckx Bram, Smeets Dominiek, Horvat Reinhard, Aust Stefanie, Hamilton Gerhard, Zeillinger Robert, Cacsire Castillo-Tong Dan
Abstract excerpt
Cancer cell lines are good in vitro models to study molecular mechanisms underlying chemoresistance and cancer recurrence. Recent works have demonstrated that most of the available ovarian cancer cell lines are most unlikely high grade serous (HGSOC), the major type of epithelial ovarian cancer. We aimed at establishing well characterized HGSOC cell lines, which can be used as optimal models for ovarian cancer...
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