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Article

Genetic Analysis of the Hsm3 Protein Function in Yeast Saccharomyces cerevisiae NuB4 Complex.

Genes - 17 Jul 2021

Evstyukhina Tatiyana A, Alekseeva Elena A, Fedorov Dmitriy V, Peshekhonov Vyacheslav T, Korolev Vladimir G

Abstract excerpt

In the nuclear compartment of yeast, NuB4 core complex consists of three proteins, Hat1, Hat2, and Hif1, and interacts with a number of other factors. In particular, it was shown that NuB4 complex physically interacts with Hsm3p. Early we demonstrated that the gene HSM3 participates in the control of replicative and reparative spontaneous mutagenesis, and that hsm3Δ mutants increase the frequency of mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34356099
DOI: 10.3390/genes12071083
PMCID: PMC8307810

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