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Article

Polymorphism in promotor region of IL6 gene as a predictor for severity in COVID -19 patients.

The Egyptian journal of immunology - 1 Apr 2022

Aladawy Shaimaa A, Adel Lamiaa A, Abdel Salam Shimaa A, Raafat Riham H, Khattab Mona A

Abstract excerpt

SARS-CoV-2 is the causative agent of coronavirus disease started in 2019 (COVID-19). IL-6 gene is located on chromosome 7. A considerable number of polymorphisms was identified in the IL-6 gene. Polymorphism in IL-6-174C allele is associated with a higher level of IL-6 production and this may lead to severity of in COVID-19 patients. We intended to investigate the role of polymorphism in the promotor region of...

Topics

COVID-19
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-6
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
SARS-CoV-2

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35436049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-35436049-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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