Article
Rare cases of medulloblastoma with hypermutation.
Cancer reports (Hoboken, N.J.) - 1 May 2022
Bagchi Aditi, Beddows Ian, Cornelius Albert, Robinson Giles W, Jewell Scott D
Abstract excerpt
BACKGROUND: Medulloblastoma is the most common malignant brain tumor of childhood and is considered a tumor with low mutational burden (~1 Mut/Mb). Therefore, though the medulloblastoma genomes have been extensively characterized in literature, reports on potential hypermutations and underlying mutagenic processes in medulloblastomas are limited. AIM: In this report, we studied the landscape of mutational burden...
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