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Molecular variants and mutations in medulloblastoma

1 Feb 2014

Abstract excerpt

Medulloblastoma is the commonest malignant brain tumor in children. Treatment with surgery, irradiation, and chemotherapy has improved outcomes in recent years, but patients are frequently left with devastating neurocognitive and other sequelae following such therapy. While the prognosis has traditionally been based on conventional histopathology and clinical staging (based on age, extent of resection, and...

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PMID: 24523595
DOI: 10.2147/pgpm.s38698

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