High-throughput suppressor screen demonstrates that RcsF monitors outer membrane integrity and not Bam complex function.

Abstract excerpt

The regulator of capsule synthesis (Rcs) is a complex signaling cascade that monitors gram-negative cell envelope integrity. The outer membrane (OM) lipoprotein RcsF is the sensory component, but how RcsF functions remains elusive. RcsF interacts with the β-barrel assembly machinery (Bam) complex, which assembles RcsF in complex with OM proteins (OMPs), resulting in RcsF's partial cell surface exposure....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial Capsules
• Share to Bacterial Outer Membrane Proteins