Article
Fine-Tuning of σE Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli.
Journal of bacteriology - 1 Jun 2019
Hart Elizabeth M, O'Connell Aileen, Tang Kimberly, Wzorek Joseph S, Grabowicz Marcin, Kahne Daniel, Silhavy Thomas J
Abstract excerpt
The Gram-negative outer membrane (OM) is a selectively permeable asymmetric bilayer that allows vital nutrients to diffuse into the cell but prevents toxins and hydrophobic molecules from entering. Functionally and structurally diverse β-barrel outer membrane proteins (OMPs) build and maintain the permeability barrier, making the assembly of OMPs crucial for cell viability. In this work, we characterize an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
