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Hemophagocytic Lymphohistiocytosis

4 Aug 2021

Abstract excerpt

CONTEXT.—: Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of immune regulation that can eventually result in end-organ damage and death. HLH is characterized by uncontrolled activation of cytotoxic T lymphocytes, natural killer cells, and macrophages that can lead to a cytokine storm. The diagnosis of HLH is often challenging due to the diverse clinical manifestations and the...

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PMID: 34347856
DOI: 10.5858/arpa.2020-0802-ra

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