Article
Diagnostic chest X-rays and breast cancer risk among women with a hereditary predisposition to breast cancer unexplained by a BRCA1 or BRCA2 mutation.
Breast cancer research : BCR - 3 Aug 2021
Ribeiro Guerra Maximiliano, Coignard Juliette, Eon-Marchais Séverine, Dondon Marie-Gabrielle, Le Gal Dorothée, Beauvallet Juana, Mebirouk Noura, Belotti Muriel, Caron Olivier, Gauthier-Villars Marion, Coupier Isabelle, Buecher Bruno, Lortholary Alain, Fricker Jean-Pierre, Gesta Paul, Noguès Catherine, Faivre Laurence, Berthet Pascaline, Luporsi Elisabeth, Delnatte Capucine, Bonadona Valérie, Maugard Christine M, Pujol Pascal, Lasset Christine, Longy Michel, Bignon Yves-Jean, Adenis-Lavignasse Claude, Venat-Bouvet Laurence, Dreyfus Hélène, Gladieff Laurence, Mortemousque Isabelle, Audebert-Bellanger Séverine, Soubrier Florent, Giraud Sophie, Lejeune-Dumoulin Sophie, Limacher Jean-Marc, Chiesa Jean, Fajac Anne, Floquet Anne, Eisinger François, Tinat Julie, Fert-Ferrer Sandra, Colas Chrystelle, Frebourg Thierry, Damiola Francesca, Barjhoux Laure, Cavaciuti Eve, Mazoyer Sylvie, Tardivon Anne, Lesueur Fabienne, Stoppa-Lyonnet Dominique, Andrieu Nadine
Abstract excerpt
BACKGROUND: Diagnostic ionizing radiation is a risk factor for breast cancer (BC). BC risk increases with increased dose to the chest and decreases with increased age at exposure, with possible effect modification related to familial or genetic predisposition. While chest X-rays increase the BC risk of BRCA1/2 mutation carriers compared to non-carriers, little is known for women with a hereditary predisposition...
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