Article
Diagnostic chest X-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2013
John Esther M, McGuire Valerie, Thomas Duncan, Haile Robert, Ozcelik Hilmi, Milne Roger L, Felberg Anna, West Dee W, Miron Alexander, Knight Julia A, Terry Mary Beth, Daly Mary, Buys Saundra S, Andrulis Irene L, Hopper John L, Southey Melissa C, Giles Graham G, Apicella Carmel, Thorne Heather, Whittemore Alice S
Abstract excerpt
BACKGROUND: The effects of low-dose medical radiation on breast cancer risk are uncertain, and few studies have included genetically susceptible women, such as those who carry germline BRCA1 and BRCA2 mutations. METHODS: We studied 454 BRCA1 and 273 BRCA2 mutation carriers ages younger than 50 years from three breast cancer family registries in the United States, Canada, and Australia/New Zealand. We estimated...
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