Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study.

doi:10.1200/JCO.2017.77.3424

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Article

Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 May 2018

Reiner Anne S, Sisti Julia, John Esther M, Lynch Charles F, Brooks Jennifer D, Mellemkjær Lene, Boice John D, Knight Julia A, Concannon Patrick, Capanu Marinela, Tischkowitz Marc, Robson Mark, Liang Xiaolin, Woods Meghan, Conti David V, Duggan David, Shore Roy, Stram Daniel O, Thomas Duncan C, Malone Kathleen E, Bernstein Leslie, Bernstein Jonine L

Abstract excerpt

Purpose The Women's Environmental Cancer and Radiation Epidemiology (WECARE) study demonstrated the importance of breast cancer family history on contralateral breast cancer (CBC) risk, even for noncarriers of deleterious BRCA1/2 mutations. With the completion of WECARE II, updated risk estimates are reported. Additional analyses that exclude women negative for deleterious mutations in ATM, CHEK2*1100delC, and...

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Identifiers

PMID: 29620998
DOI: 10.1200/JCO.2017.77.3424
PMCID: PMC5959199

Genes

AR
BRCA1
ATM
CHEK2
PALB2
UBC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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