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The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis

7 Jul 2021

Abstract excerpt

Elongation of vascular endothelial cells (ECs) is an important process in angiogenesis; however, the molecular mechanisms remain unknown. The actin-crosslinking protein TAGLN (transgelin, also known as SM22 or SM22α) is abundantly expressed in smooth muscle cells (SMCs) and is widely used as a canonical marker for this cell type. In the course of studies using mouse embryonic stem cells (ESCs) carrying an Tagln...

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PMID: 34338296
DOI: 10.1242/jcs.254920

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