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Multifaceted role of transgelin isoforms in cancer hallmarks

1 Feb 2025

Abstract excerpt

Transgelins (TAGLNs) are actin-binding proteins within the calponin family, playing a crucial role in modulating actin-myosin interactions and maintaining actin filament stability. These proteins are expressed in both smooth and non-smooth muscle cells, contributing to the regulation of muscle contractility and cell migration. TAGLNs family has three isoforms that differ in their isoelectric point, namely:...

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PMID: 40102702
DOI: 10.1093/carcin/bgaf014

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