Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition

30 Nov 2018

Abstract excerpt

Endothelial cell (EC) plasticity in pathological settings has recently been recognized as a driver of disease progression. Endothelial-to-mesenchymal transition (EndMT), in which ECs acquire mesenchymal properties, has been described for a wide range of pathologies, including cancer. However, the mechanism regulating EndMT in the tumor microenvironment and the contribution of EndMT in tumor progression are not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Congenital heart defects research
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30500808
DOI: 10.1371/journal.pgen.1007826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transitionPMID 30500808Read ↗

Synergistic Role of Endothelial ERG and FLI1 in Mediating Pulmonary Vascular HomeostasisSemantic proximity Read ↗

Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human DiseasesSemantic proximity Read ↗

Endothelial to mesenchymal transition: at the axis of cardiovascular health and diseaseSemantic proximity Read ↗

Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial DysfunctionSemantic proximity Read ↗

Endothelial Erg Regulates Expression of Pulmonary Lymphatic Junctional and Inflammation Genes in Mouse Lungs Impacting Lymphatic TransportSemantic proximity Read ↗

Endothelial Erg Regulates Expression of Pulmonary Lymphatic Junctional and Inflammation Genes in Mouse Lungs Impacting Lymphatic TransportSemantic proximity Read ↗

Identification and functional role of endothelial isoforms of the transcription factor ERGSemantic proximity Read ↗

The transcription factor ERG is a gatekeeper of endothelial cell homeostasisSemantic proximity Read ↗

Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosisSemantic proximity Read ↗

The therapeutic potential of targeting the endothelial-to-mesenchymal transitionSemantic proximity Read ↗

Endothelial-to-mesenchymal transition: A novel therapeutic target for cardiovascular diseases.Semantic proximity Read ↗

ETS1, a target gene of the EWSR1::FLI1 fusion oncoprotein, regulates the expression of the focal adhesion protein TENSIN3Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.