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PPARGC1A promoter DNA-methylation level and glucose metabolism in Ecuadorian women with Turner syndrome.

Hormone molecular biology and clinical investigation - 22 Dec 2020

Álvarez-Nava Francisco, Salinas Marco, Bastidas Daniela, Vicuña Yosselin, Racines-Orbe Marcia

Abstract excerpt

OBJECTIVES: Reduced gene expression of PPARGC1A in subjects with insulin resistance (IR) has been reported. Insulin resistance occurs early on the course of Turner syndrome (TS). The main objective of this study was to evaluate the relationship between PPARGC1A promoter DNA methylation status in lymphocytes and insulin sensitivity and secretion in Ecuadorian females with TS. METHODS: We examined a cohort of 34...

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Identifiers

PMID: 34332520
DOI: 10.1515/hmbci-2020-0076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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