Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic regulation of an adverse metabolic phenotype in polycystic ovary syndrome: the impact of the leukocyte methylation of PPARGC1A promoter.

Fertility and sterility - 1 Feb 2017

Zhao Hongcui, Zhao Yue, Ren Yun, Li Min, Li Tianjie, Li Rong, Yu Yang, Qiao Jie

Abstract excerpt

OBJECTIVE: To investigate PPARGC1A promoter methylation and mitochondria DNA (mtDNA) content in the leukocytes of women with polycystic ovary syndrome (PCOS) and analyze the relationship between these indices and metabolic risk for women with PCOS. DESIGN: Cross-sectional study. SETTING: University hospital. PATIENT(S): A total of 175 women with PCOS and 127 healthy controls. INTERVENTION(S): None. MAIN OUTCOME...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Sectional Studies
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Epigenesis, Genetic

Share to Hospitals, University

Share to Leukocytes

Share to Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

Share to Polycystic Ovary Syndrome

Source

Identifiers

PMID: 27889100
DOI: 10.1016/j.fertnstert.2016.10.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic regulation of an adverse metabolic phenotype in polycystic ovary syndrome: the impact of the leukocyte methylation of PPARGC1A promoter.PMID 27889100Read ↗

DNA methylation in polycystic ovary syndrome: Emerging evidence and challengesSemantic proximity Read ↗

DNA methylation in the pathogenesis of polycystic ovary syndromeSemantic proximity Read ↗

The epigenomics of polycystic ovarian syndrome: from pathogenesis to clinical manifestationsSemantic proximity Read ↗

Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary SyndromeSemantic proximity Read ↗

Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary SyndromeSemantic proximity Read ↗

Polymorphisms in the TFAM and PGC1-α genes and their association with polycystic ovary syndrome among South Indian women.Semantic proximity Read ↗

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women.Semantic proximity Read ↗

Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis.Semantic proximity Read ↗

Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.Semantic proximity Read ↗

Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndromeSemantic proximity Read ↗

Intrauterine Reprogramming of the Polycystic Ovary Syndrome: Evidence from a Pilot Study of Cord Blood Global Methylation AnalysisSemantic proximity Read ↗

Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary SyndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.