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Article

Links between thyroid hormone action, oxidative metabolism, and diabetes risk?

Thyroid : official journal of the American Thyroid Association - 1 Feb 2008

Crunkhorn Sarah, Patti Mary-Elizabeth

Abstract excerpt

A key phenotype associated with type 2 diabetes in humans is impaired mitochondrial oxidative metabolism in skeletal muscle, a pattern potentially contributing to increased lipid accumulation and impaired metabolic flexibility-in turn, central features of both insulin resistance and diabetes. Since thyroid hormone regulates mitochondrial gene expression and function in skeletal muscle, reductions in T3-mediated...

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Share to Diabetes Mellitus, Type 2
Share to Iodide Peroxidase
Share to Mitochondria, Muscle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

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Share to Receptors, Thyroid Hormone

Share to Thyroid Hormones

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Source

Identifiers

PMID: 18279023
DOI: 10.1089/thy.2007.0249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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