Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere Shortening and Fusions: A Link to Aneuploidy in Early Human Embryo Development

1 Jul 2021

Abstract excerpt

ABSTRACT Importance It is known that oocytes undergo aging that is caused by exposure to an aged ovarian microenvironment. Telomere length in mouse and bovine oocytes declines with age, and age-associated telomere shortening in oocytes is considered a sign of poor development competency. Women with advanced age undergoing assisted reproductive technologies have poor outcomes because of increasing aneuploidy rates...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prenatal Screening and Diagnostics
Share to Reproductive Biology and Fertility
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34324695
DOI: 10.1097/ogx.0000000000000907

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere Shortening and Fusions: A Link to Aneuploidy in Early Human Embryo DevelopmentPMID 34324695Read ↗

Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryosSemantic proximity Read ↗

Insights into the Role of Telomeres in Human Embryological Parameters. Opinions Regarding IVFSemantic proximity Read ↗

Telomere DNA Deficiency Is Associated with Development of Human Embryonic AneuploidySemantic proximity Read ↗

Telomere Length Reprogramming in Embryos and Stem CellsSemantic proximity Read ↗

The telomere theory of reproductive senescence in womenSemantic proximity Read ↗

Oxidative Stress Induces Telomere Dysfunction and Shortening in Human Oocytes of Advanced Age DonorsSemantic proximity Read ↗

Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian speciesSemantic proximity Read ↗

Alteration of relative telomere length and telomerase reverse transcriptase expression in the granulosa cells of women during aging and assessment of in vitro fertilization outcomesSemantic proximity Read ↗

Evaluation of telomere length in cumulus cells as a potential biomarker of oocyte and embryo qualitySemantic proximity Read ↗

Aneuploidy and early human embryo developmentSemantic proximity Read ↗

Telomere lengths in human oocytes, cleavage stage embryos and blastocystsSemantic proximity Read ↗

Origins and mechanisms leading to aneuploidy in human eggsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.