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Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species

8 Aug 2013

Abstract excerpt

Telomeres are located at the ends of all eukaryotic chromosomes and protect them from deleterious events such as inappropriate DNA repair, illegitimate recombination or improper segregation of the chromosomes during mitotic or meiotic divisions. However, telomeres gradually shorten primarily due to successive rounds of genomic DNA replication and also as the result of the adverse effects of oxidative stress,...

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Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence
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PMID: 23928157
DOI: 10.1093/molehr/gat055

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