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Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos

3 Jul 2023

Abstract excerpt

Telomeres are repetitive DNA sequences at eukaryotic chromosome ends and function in maintaining genome integrity and stability. These unique structures undergo shortening due to various factors including biological aging, consecutive DNA replication, oxidative stress, and genotoxic agents. Shortened telomeres can be lengthened by the enzyme telomerase and alternative lengthening of telomeres in germ cells, early...

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PMID: 37400833
DOI: 10.1186/s13048-023-01211-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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