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Article

Enhancement of heterologous protein production in Corynebacterium glutamicum via atmospheric and room temperature plasma mutagenesis and high-throughput screening.

Journal of biotechnology - 20 Sept 2021

Meng Lihong, Gao Xiong, Liu Xiuxia, Sun Manman, Yan Hao, Li An, Yang Yankun, Bai Zhonghu

Abstract excerpt

Atmospheric and room temperature plasma (ARTP) is a new and efficient mutation breeding technique. In this study, we discuss a strategy combining ARTP mutagenesis and high-throughput screening to engineer Corynebacterium glutamicum towards high yield production of heterologous proteins. First, three target strains, MC2, MA8, and MA6, were screened from the mutant library with enhanced green fluorescent protein...

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PMID: 34311028
DOI: 10.1016/j.jbiotec.2021.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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