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Assessment of quality attributes for adeno‐associated viral vectors

26 Jul 2021

Abstract excerpt

There is a strong and growing interest in the development and production of gene therapy products, including those utilizing adeno-associated virus (AAV) particles. This is evident with the increase in the number of clinical trials and agency approvals for AAV therapeutics. As bioproduction of AAV viral vectors matures, a quality by design (QbD) approach to process development can aid in process robustness and...

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PMID: 34309017
DOI: 10.1002/bit.27905

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