Article
Suggestive evidence of genetic association of -572G > C polymorphism with primary open angle glaucoma in a North Indian Punjabi population.
Human immunology - 1 Oct 2021
Thakur Nanamika, Kumar Pandey Rajeev, Kumar Vipin, Mannan Rashim, Pruthi Archna, Mehrotra Sanjana
Abstract excerpt
BACKGROUND: IL6 is an important candidate gene implicated in the pathogenesis of glaucoma. The present study assessed the genetic association of -174G > C and -572G > C polymorphisms in the IL6 promoter region with primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) in a north Indian Punjabi cohort. METHODS: 910 subjects (313 POAG, 148 PACG cases and 449 controls) were recruited....
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