Article
Association of TGFB -509C>T promoter polymorphism with primary angle closure glaucoma in a North Indian Punjabi cohort.
BMC ophthalmology - 8 Apr 2021
Thakur Nanamika, Pandey Rajeev Kumar, Mannan Rashim, Pruthi Archna, Mehrotra Sanjana
Abstract excerpt
PURPOSE: Transforming growth factor beta (TGFB) is an important candidate gene implicated in glaucoma pathogenesis because it affects retinal ganglionic cell survival. The present study assessed the genetic association of -509C > T variant in the TGFB promoter region with primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) in a North Indian Punjabi population. METHOD: A total of 867...
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