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Article

Polymorphism rs10483727 in the SIX1/SIX6 Gene Locus Is a Risk Factor for Primary Open Angle Glaucoma in a Saudi Cohort.

Genetic testing and molecular biomarkers - 1 Jan 2018

Kondkar Altaf A, Azad Taif A, Almobarak Faisal A, Kalantan Hatem, Sultan Tahira, Alsabaani Nasser A, Al-Obeidan Saleh A, Abu-Amero Khaled K

Abstract excerpt

AIMS: Variant rs10483727 in the SIX1/SIX6 locus has been significantly associated with primary open angle glaucoma (POAG) in multiple ethnic groups. We conducted a case-control study to investigate the association between this variant and POAG in a Saudi cohort. MATERIALS AND METHODS: Polymorphism rs10483727 was genotyped by using a TaqMan® assay in 186 subjects comprising 92 unrelated POAG cases and 94 controls...

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Source

Identifiers

PMID: 29190129
DOI: 10.1089/gtmb.2017.0159

Genes

SIX1
SIX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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