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Article

Can Physical Activity Reduce the Risk of Cognitive Decline in Apolipoprotein e4 Carriers? A Systematic Review.

International journal of environmental research and public health - 6 Jul 2021

Perez-Lasierra Jose Luis, Casajús Jose Antonio, Casasnovas José Antonio, Arbones-Mainar Jose Miguel, Lobo Antonio, Lobo Elena, Moreno-Franco Belén, Gonzalez-Agüero Alejandro

Abstract excerpt

Physical activity (PA) reduces the risk of cognitive decline (CD) in the general population. However, little is known about whether the presence of the apolipoprotein E epsilon 4 allele (APOE e4) could modify this beneficial effect. The aim of this systematic review was to analyze and synthetize the scientific evidence related to PA levels and CD risk in cognitively healthy APOE e4 carriers. Four electronic...

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Source

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Identifiers

PMID: 34299687
DOI: 10.3390/ijerph18147238
PMCID: PMC8303365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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