Article
Mitochondrial Heteroplasmy Shifting as a Potential Biomarker of Cancer Progression.
International journal of molecular sciences - 9 Jul 2021
Pérez-Amado Carlos Jhovani, Bazan-Cordoba Amellalli, Hidalgo-Miranda Alfredo, Jiménez-Morales Silvia
Abstract excerpt
Cancer is a serious health problem with a high mortality rate worldwide. Given the relevance of mitochondria in numerous physiological and pathological mechanisms, such as adenosine triphosphate (ATP) synthesis, apoptosis, metabolism, cancer progression and drug resistance, mitochondrial genome (mtDNA) analysis has become of great interest in the study of human diseases, including cancer. To date, a high number...
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