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Article

The control of interferon-inducible gene expression.

FEBS letters - 22 Jul 1991

Kerr I M, Stark G R

Abstract excerpt

The alpha beta interferons (IFNs) transiently induce genes through an IFN-stimulable DNA response element (ISRE). IFN-cell surface receptor interaction triggers the cytoplasmic activation of the complex primary transcription factor E, which on translocation and interaction with the ISRE initiates transcription. Whether E is activated directly through the receptor(s) or through a more classical second message...

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Identifiers

PMID: 1713174
DOI: 10.1016/0014-5793(91)80802-a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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