Article
The control of interferon-inducible gene expression.
FEBS letters - 22 Jul 1991
Kerr I M, Stark G R
Abstract excerpt
The alpha beta interferons (IFNs) transiently induce genes through an IFN-stimulable DNA response element (ISRE). IFN-cell surface receptor interaction triggers the cytoplasmic activation of the complex primary transcription factor E, which on translocation and interaction with the ISRE initiates...
Topics
- Base Sequence
- Gene Expression Regulation
- Interferons
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Regulatory Sequences, Nucleic Acid
- Signal Transduction
- Transcription Factors
- Viral Interference
