Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exome sequencing identifies novel somatic variants in African American esophageal squamous cell carcinoma.

Scientific reports - 20 Jul 2021

Erkizan Hayriye Verda, Sukhadia Shrey, Natarajan Thanemozhi G, Marino Gustavo, Notario Vicente, Lichy Jack H, Wadleigh Robert G

Abstract excerpt

Esophageal cancer has a strikingly low survival rate mainly due to the lack of diagnostic markers for early detection and effective therapies. In the U.S., 75% of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) are of African descent. African American ESCC (AA ESCC) is particularly aggressive, and its biological underpinnings remain poorly understood. We sought to identify the genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to DNA Mutational Analysis

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Exome Sequencing

Share to Genetic Predisposition to Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 34285259
DOI: 10.1038/s41598-021-94064-0
PMCID: PMC8292420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exome sequencing identifies novel somatic variants in African American esophageal squamous cell carcinoma.PMID 34285259Read ↗

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.Semantic proximity Read ↗

Whole-exome sequencing identified mutational profiles of squamous cell carcinomas of anus.Semantic proximity Read ↗

Identification of genomic alterations in oesophageal squamous cell cancer.Semantic proximity Read ↗

Subtyping sub-Saharan esophageal squamous cell carcinoma by comprehensive molecular analysis.Semantic proximity Read ↗

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patientsSemantic proximity Read ↗

Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Genetic landscape of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Somatic mutations of esophageal adenocarcinoma: a comparison between Black and White patients.Semantic proximity Read ↗

Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomasSemantic proximity Read ↗

Characterizing the mutational landscape of sinonasal squamous cell carcinoma using whole-exome sequencing.Semantic proximity Read ↗

Identification of novel mutations by exome sequencing in African American colorectal cancer patients.Semantic proximity Read ↗

Whole-Exome Profiling of NSCLC Among African Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.