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Article

Identification of novel mutations by exome sequencing in African American colorectal cancer patients.

Cancer - 1 Jan 2015

Ashktorab Hassan, Daremipouran Mohammad, Devaney Joe, Varma Sudhir, Rahi Hamed, Lee Edward, Shokrani Babak, Schwartz Russell, Nickerson Michael L, Brim Hassan

Abstract excerpt

BACKGROUND: The purpose of this study was to identify genome-wide single nucleotide variants and mutations in African American patients with colorectal cancer (CRC). There is a need of such studies in African Americans, because they display a higher incidence of aggressive CRC tumors. METHODS: We performed whole exome sequencing (WES) on DNA from 12 normal/tumor pairs of African American CRC patient tissues. Data...

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Identifiers

PMID: 25250560
DOI: 10.1002/cncr.28922
PMCID: PMC4296906

Genes

APC
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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