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Sequencing for germline mutations in Swedish breast cancer families reveals novel breast cancer risk genes.

Scientific reports - 19 Jul 2021

Helgadottir Hafdis T, Thutkawkorapin Jessada, Lagerstedt-Robinson Kristina, Lindblom Annika

Abstract excerpt

Identifying genetic cancer risk factors will lead to improved genetic counseling, cancer prevention and cancer care. Analyzing families with a strong history of breast cancer (BC) has been a successful method to identify genes that contribute to the disease. This has led to discoveries of high-risk genes like the BRCA-genes. Nevertheless, many BC incidences are of unknown causes. In this study, exome sequencing...

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Identifiers

PMID: 34282249
DOI: 10.1038/s41598-021-94316-z
PMCID: PMC8289997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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