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Article

Familial breast cancer.

Clinical genetics - 1 Aug 2012

Lalloo F, Evans D G

Abstract excerpt

Since the localization and discovery of the first high-risk breast cancer (BC) genes in 1990, there has been a substantial progress in unravelling its familial component. Increasing numbers of women at risk of BC are coming forward requesting advice on their risk and what they can do about it. Three groups of genetic predisposition alleles have so far been identified with high-risk genes conferring 40-85%...

Topics

Breast Neoplasms
Family
Female
Genes, BRCA1
Genes, BRCA2
Genes, p53
Genetic Predisposition to Disease
Humans
Penetrance

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22356477
DOI: 10.1111/j.1399-0004.2012.01859.x

Genes

BRCA1
BRCA2
ATM
CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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