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Article

Breast cancer genome-wide association studies: there is strength in numbers.

Oncogene - 26 Apr 2012

Fanale D, Amodeo V, Corsini L R, Rizzo S, Bazan V, Russo A

Abstract excerpt

Breast cancer (BC) is a heterogeneous disease that exhibits familial aggregation. Family linkage studies have identified high-penetrance genes, BRCA1, BRCA2, PTEN and TP53, that are responsible for inherited BC syndromes. Moreover, a combination of family-based and population-based approaches indicated that genes involved in DNA repair, such as CHEK2, ATM, BRIP and PALB2, are associated with moderate risk....

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Source

Identifiers

PMID: 21996731
DOI: 10.1038/onc.2011.408

Genes

BRCA1
BRCA2
FGFR2
LSP1
MAP3K1
ATM
CHEK2
PALB2
PTEN
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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