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Article

No effect of deleted in malignant brain tumors 1 deficiency on chemotherapy induced murine intestinal mucositis.

Scientific reports - 19 Jul 2021

Nexoe Anders B, Pedersen Andreas A, von Huth Sebastian, Sorensen Grith L, Holmskov Uffe, Jiang Ping-Ping, Detlefsen Sönke, Husby Steffen, Rathe Mathias

Abstract excerpt

Mucositis is a serious adverse effect of chemotherapeutic treatment. During intestinal mucositis, the mucosal barrier is compromised, increasing the risk of severe infections. Mucositis necessitates dose reduction or pauses in treatment, which affect the outcome of the treatment. Deleted in malignant brain tumors 1 (DMBT1) is a secreted scavenger protein with effects on innate immunity and epithelial...

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Identifiers

PMID: 34282203
DOI: 10.1038/s41598-021-94076-w
PMCID: PMC8289998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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