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Article

Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor‑promoting factors (Review).

Oncology reports - 1 Aug 2021

Wang Zhengyi, Wu Xiaoying

Abstract excerpt

Recent studies have found that somatic gene mutations and environmental tumor‑promoting factors are both indispensable for tumor formation. Telomeric repeat‑binding factor (TRF)2 is the core component of the telomere shelterin complex, which plays an important role in chromosome stability and the maintenance of normal cell physiological states. In recent years, TRF2 and its role in tumor formation have gradually...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34278498
DOI: 10.3892/or.2021.8135
PMCID: PMC8273685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Abnormal function of telomere protein TRF2 induces cell mutation and the effects of environmental tumor‑promoting factors (Review).PMID 34278498Read ↗

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