Article
Next-Generation Sequencing and Triple-Negative Breast Cancer: Insights and Applications.
International journal of molecular sciences - 2 Jun 2023
Tierno Domenico, Grassi Gabriele, Scomersi Serena, Bortul Marina, Generali Daniele, Zanconati Fabrizio, Scaggiante Bruna
Abstract excerpt
The poor survival of triple-negative breast cancer (TNBC) is due to its aggressive behavior, large heterogeneity, and high risk of recurrence. A comprehensive molecular investigation of this type of breast cancer using high-throughput next-generation sequencing (NGS) methods may help to elucidate its potential progression and discover biomarkers related to patient survival. In this review, the NGS applications in...
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