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Article

Multi-Gene Testing Overview with a Clinical Perspective in Metastatic Triple-Negative Breast Cancer.

International journal of molecular sciences - 1 Jul 2021

Dameri Martina, Ferrando Lorenzo, Cirmena Gabriella, Vernieri Claudio, Pruneri Giancarlo, Ballestrero Alberto, Zoppoli Gabriele

Abstract excerpt

Next-generation sequencing (NGS) is the technology of choice for the routine screening of tumor samples in clinical practice. In this setting, the targeted sequencing of a restricted number of clinically relevant genes represents the most practical option when looking for genetic variants associated with cancer, as well as for the choice of targeted treatments. In this review, we analyze available NGS platforms...

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Identifiers

PMID: 34281208
DOI: 10.3390/ijms22137154
PMCID: PMC8268401

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