Article
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
Haematologica - 1 May 2022
Papaioannou Dimitrios, Ozer Hatice G, Nicolet Deedra, Urs Amog P, Herold Tobias, Mrózek Krzysztof, Batcha Aarif M N, Metzeler Klaus H, Yilmaz Ayse S, Volinia Stefano, Bill Marius, Kohlschmidt Jessica, Pietrzak Maciej, Walker Christopher J, Carroll Andrew J, Braess Jan, Powell Bayard L, Eisfeld Ann-Kathrin, Uy Geoffrey L, Wang Eunice S, Kolitz Jonathan E, Stone Richard M, Hiddemann Wolfgang, Byrd John C, Bloomfield Clara D, Garzon Ramiro
Abstract excerpt
Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the nucleotide sequences of lncRNA in AML patients is unknown. Herein, we analyzed total RNA sequencing data of 377 younger adults (aged <60 years) with CN-AML, who were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.