Article
Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients.
Haematologica - 1 Oct 2017
De Clara Etienne, Gourvest Morgane, Ma Hanjing, Vergez François, Tosolini Marie, Dejean Sébastien, Demur Cécile, Delabesse Eric, Recher Christian, Touriol Christian, Martelli Maria Paola, Falini Brunangelo, Brousset Pierre, Bousquet Marina
Abstract excerpt
Long non-coding RNAs are defined as transcripts larger than 200 nucleotides but without protein-coding potential. There is growing evidence of the important role of long non-coding RNAs in cancer initiation, development and progression. In this study, we sought to evaluate the long non-coding RNA expression profile of patients with cytogenetically normal acute myeloid leukemia (AML). RNA-sequencing of 40...
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